Guide to Current Research in Victorian Universities Department of State and Regional Development
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The University of Melbourne

http://www.unimelb.edu.au/research
The University of Melbourne Contacts Page
Contact Details

The University of Melbourne is an international, research-led university with more than 34,000 students, including some 9,000 postgraduates, 2,500 research higher degree students, and 3,400 international students from over 70 countries.

Victoria's first university, and Australia's second oldest university, Melbourne's tradition of excellence in research, teaching and learning, and service to the community dates back to 1855.

Australia's national benchmark of research performance, the National Composite Index, saw Melbourne again achieve the highest ranking among Australian universities for 2000.

The University is at the centre of the Parkville Triangle, Australia's most highly concentrated Knowledge Precinct of hospitals, university campuses, research institutes and private sector knowledge-based industries.

With campuses close to the Melbourne Central Business District and in regional Victoria, the University is engaged in a wide variety of partnerships with educational institutions, government and industry. It is a founding member of Universitas 21, a network of 18 research-intensive universities in 10 countries, a leader in Bio21, a $400m initial stage program to establish Victoria as one of the world's leading biotechnology centres, a participant in 15 Cooperative Research Centres (CRC), and a partner in our wide range of other collaborative research initiatives. Melbourne Enterprise International Ltd and Melbourne University Private Limited are two key vehicles for promoting partnerships in the delivery of high-quality educational services and commercial business development.

Melbourne welcomes the opportunity to engage with, support, and develop partnerships with small, medium and large public and private enterprises, for example, through contract research and development, development and commercialisation of new technologies, provision of expert advice, consultancies, graduate recruitment, student placement, staff secondment and exchanges, sponsorship of research and scholarships, and joint research projects.

For further information, including weekly news from the University, please visit www.unimelb.edu.au/visitor/. To discuss research opportunities, services and partnerships, contact the Melbourne Research and Innovation Officecrozierb@unimelb.edu.au

 

Austin and Repatriation Medical Centre
Department of Medicine
http://www.medarmc.unimelb.edu.au/Prosstudent.html
[ Australian Science at Work Entry ]

Insulin-like growth factor (IGF)-II binding specificity of IGF binding protein-6: Structural and functional studies
Chief Researcher: Bach L A
Duration: 2000 - 2002
Descriptor: PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


The biology of vasopressin in cardiovascular homeostasis and disease
Chief Researcher: Burrell L
Duration: 1999 - 2003
Descriptors: CARDIOVASCULAR; ENDOCRINE; HORMONE
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Blockade of vasoactive hormones in diabetic nephropathy
Chief Researcher: Cooper M E
Duration: 1999 - 2001
Descriptors: DIABETES; ENDOCRINE
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Cellular and molecular mechanisms of axonal sprouting in the CNS
Chief Researcher: Howells D W
Duration: 1999 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


New dopaminergic neurons in the Parkinson's disease striatum: Establishment of phenotype, function and origin
Chief Researcher: Howells D W
Duration: 2001 - 2005
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Approaches to allogeneic chimerism for the induction of transplantation tolerance
Chief Researcher: Ierino F L
Duration: 2001 - 2003
Descriptor: TRANPLANTATION
Research Field Classification: 320205 Transplantation Immunology


Role of glycation and its receptors in diabetic complications
Chief Researcher: Jerums G
Duration: 1999 - 2001
Descriptors: DIABETES; RECEPTORS
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


HB-EGF promotes recovery from experimental acute renal failure
Chief Researcher: Power D A
Duration: 2000 - 2002
Descriptors: DISEASE--ENDOCRINE;--RENAL
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Structural and functional consequences of a human nicotinic receptor mutation
Chief Researcher: Reutens D C
Duration: 2000 - 2002
Descriptor: RECEPTOR MUTATION
Research Field Classification: 270201 Gene Expression


Definition of the genetic abnormality in thin basement membrane disease (TBMD)
Chief Researcher: Savige J A
Duration: 1999 - 2001
Descriptor: DISEASE--GENE
Research Field Classification: 270201 Gene Expression


Genetics of generalized epilepsy
Chief Researcher: Scheffer I E
Duration: 2001 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Genetic and environmental determinants of bone size, mass and density: A twin study of growth
Chief Researcher: Seeman E
Duration: 1999 - 2001
Descriptors: GENE--BONE
Research Field Classification: 270201 Gene Expression


Identification of brain neurons involved in the cardiovascular response to fear and flight
Chief Researcher: Verberne A J
Duration: 2000 - 2004
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


The renal components of the amylin system: Physiological and pathophysiological implications
Chief Researcher: Wookey P J
Duration: 1998 - 2002
Descriptor: RENAL
Research Field Classification: 320307 Medical Biochemistry: Other


The pathogenesis of motor neuron degeneration caused by a triplet repeat expansion in the androgen receptor gene
Chief Researcher: Zajac J D
Duration: 2000 - 2002
Descriptor: GENE RECEPTOR--NEURON
Research Field Classification: 320703 Peripheral Nervous System

 

Department of Surgery
[ Australian Science at Work Entry ]

Functional relationships of gastrin and its regulators in the developing and diseased gastrointestinal tracts
Chief Researcher: Shulkes A A
Duration: 2000 - 2004
Descriptor: GASTROINTESTINAL ENDOCRINE REGULATION
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


The gastrin-binding protein: A common target for gastrin and fibroblast growth factor-2 in colorectal cancer
Chief Researcher: Baldwin G S
Duration: 1999 - 2001
Descriptor: CANCER--PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


The role of autocrine progastrin and progastrin receptors in colorectal carcinoma cell growth
Chief Researcher: Baldwin G S
Duration: 1998 - 2002
Descriptor: CANCER--PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides

 

Faculty of Medicine, Dental and Health Services
School of Dental Science
http://www.dent.unimelb.edu.au/research.htm
[ Australian Science at Work Entry ]

Iron/hemin transport systems of Porphyromonas gingivalis
Chief Researcher: Reynolds E C
Duration: 2001 - 2003
Descriptor: DENTAL INFECTION
Research Field Classification: 320307 Medical Biochemistry: Other


Cell surface protein antigens of Porphyromonas gingivalis
Chief Researcher: Reynolds E C
Duration: 2000 - 2002
Descriptor: DENTAL INFECTION; PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Protease-haemaglutin complex and peptide transport in Porphyromonas gingivalis
Chief Researcher: Reynolds E C
Duration: 1999 - 2001
Descriptors: DENTAL INFECTION; ENZYME
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Characterisation of a novel amorphous calcium fluoride phosphate stabilised by phosphopeptides
Chief Researcher: Reynolds E C
Duration: 1999 - 2001
Descriptor: DENTAL ANTICANIOGENIC
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Characterisation of proteins involved in biomineralisation processes
Chief Researcher: Reynolds E C
Duration: 2000 - 2002
Descriptor: DENTAL PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


A clinical and experimental study of the biomechanical factors associated with tooth destruction
Chief Researcher: Tyas M J
Duration: 2001 - 2003
Descriptor: DENTAL
Research Field Classification: 291504 Biomechanical Engineering


A clinical trial of the anticariogenicity of casein phosphopeptide amorphous calcium phosphate in adolescents
Chief Researcher: Morgan M V
Duration: 1999 - 2001
Descriptors: ANTICANIOGEN; DENTAL; PEPTICLE
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides

 

Royal Melbourne Hospital and Western Hospital
Department of Medicine
http://medicine.medrmh.unimelb.edu.au/rmh-research.htm
[ Australian Science at Work Entry ]

The role of fructose-1,6-bisphosphatase on the regulation of hepatic gluconeogenesis
Chief Researcher: Andrikopoulos S
Duration: 2001 - 2003
Descriptors: ENZYME; PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Investigations of beta cell dysfunction and death in type 2 diabetes
Chief Researcher: Andrikopoulos S
Duration: 2000 - 2002
Descriptor: DISEASE--CONGENITAL
Research Field Classification: 320307 Medical Biochemistry: Other


Molecular analysis of interaction of P. falciparum infected erythrocytes with glycosaminoglycans
Chief Researcher: Brown G V
Duration: 2001 - 2003
Descriptors: DISEASE; INFECTION
Research Field Classification: 320405 Medical Parasitology


The adverse effects of diabetes on stroke: An echoplanar MRI study
Chief Researcher: Davis S M
Duration: 2001 - 2003
Descriptors: CARDIOVASCULAR; DIABETES
Research Field Classification: 320702 Central Nervous System


Glomerular intracellular signalling by altered cell-matrix interactions in diabetes
Chief Researcher: Dunlop M E
Duration: 1997 - 2001
Descriptor: DIABETES
Research Field Classification: 320307 Medical Biochemistry: Other


Elucidation of mechanisms by which fibre promotes or protects from colorectal tumorigenesis
Chief Researcher: Gibson P R
Duration: 2001 - 2003
Descriptor: TUMOUR--COLORECTAL
Research Field Classification: 320307 Medical Biochemistry: Other


Mechanisms of action of the trefoil peptides in promoting healing in models of inflammatory bowel disease
Chief Researcher: Giraud A S
Duration: 2000 - 2002
Descriptor: BOWEL--INFLAMMATION
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Studies of NF-E4, a novel fetal/erythroid specific factor involve fetal globin gene regulation
Chief Researcher: Jane S M
Duration: 2000 - 2004
Descriptor: GENE--REGULATION
Research Field Classification: 270201 Gene Expression


Structure of the zinc-binding domains of the early endosomal effector EEA1 by heteronuclear NMR spectroscopy
Chief Researcher: Gooley P R
Duration: 1999 - 2001
Descriptor: CELL--SIGNALLING
Research Field Classification: 320307 Medical Biochemistry: Other


Persistent particles and monocyte/macrophage function
Chief Researcher: Hamilton J A
Duration: 2000 - 2002
Descriptor: INFLAMMATION
Research Field Classification: 320307 Medical Biochemistry: Other


Control of monocyte/macrophage function by CSF-1
Chief Researcher: Hamilton J A
Duration: -2005
Descriptor: INFLAMMATION
Research Field Classification: 320307 Medical Biochemistry: Other


Regulation of macrophage lineage differentiation
Chief Researcher: Hamilton J A
Duration: 2001 - 2003
Descriptor: INFLAMMATION
Research Field Classification: 320307 Medical Biochemistry: Other


Genetic and metabolic determinants of spontaneous physical activity
Chief Researcher: Thorburn A W
Duration: 2000 - 2002
Descriptor: GENETICS
Research Field Classification: 270201 Gene Expression


Mechanisms of gastric mucosal adaptation and repair
Chief Researcher: Yeomans N D
Duration: 1999 - 2001
Descriptor: GASTROINTESTINAL ENDOCRINE REGULATION
Research Field Classification: 320307 Medical Biochemistry: Other

 

Department of Surgery
http://www.medfac.unimelb.edu.au:81/
[ Australian Science at Work Entry ]

Cytokine and growth factor induced STAT activation and macrophage differentiation
Chief Researcher: Novak U
Duration: 1997 - 2001
Descriptor: CYLEKINE INFLAMMATION
Research Field Classification: 320307 Medical Biochemistry: Other


The role of Ryk/AF6/Eph complexes in neuronal pathfinding/fasciculation
Chief Researcher: Hovens C
Duration: 2001 - 2003
Descriptor: NEURON NEUROSCIENCE
Research Field Classification: 320307 Medical Biochemistry: Other

 

School of Behavioural Science
Department of Psychology
[ Australian Science at Work Entry ]

An fMRI investigation of colour - graphemic synaesthesia
Chief Researcher: Rich A (PhD)
Supervisor: Mattingley Dr J
Current Status: Ongoing
Descriptor: NEUROSCIENCE
Research Field Classification: 320799 Neurosciences nec


Development of executive functions in children with frontal lobe lesions
Chief Researcher: Anderson V A
Duration: 2000 - 2002
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System

 

School of Medicine
Department of Anatomy and Cell Biology
http://www.anatomy.unimelb.edu.au/research/index.htm
[ Australian Science at Work Entry ]

Tubule-interstitial interactions in renal development
Chief Researcher: Alcorn D G
Duration: 1999 - 2001
Descriptor: RENAL DEVELOPMENT
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Determination of sympathetic preganglionic neuronal phenotype
Chief Researcher: Anderson C R
Duration: 2001 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320705 Sensory Systems


A model of muscle development and tumorigenesis: The role of Stim1
Chief Researcher: Dziadek M A
Duration: 1999 - 2001
Descriptors: CANCER--TUMOUR
Research Fields Classification: 320307 Medical Biochemistry: Other


Regulation of brain development by members of the fibroblast growth factor family
Chief Researcher: Ford-Perriss M D
Duration: 2000 - 2002
Descriptor: NEUROSCIENCE--ENDOCRINE
Research Field Classification: 320702 Central Nervous System


Participation of intrinsic sensory neurons in the initiation of colonic and gastric reflexes
Chief Researcher: Furness J B
Duration: 2000 - 2002
Descriptor: NEURON--GASTROINTESTINAL
Research Field Classification: 320705 Sensory Systems


Long term changes in excitability of enteric neurons
Chief Researcher: Furness J B
Duration: 2000 - 2002
Descriptor: NEURON--PHYSIOLOGY
Research Field Classification: 320703 Peripheral Nervous System


Neural signals from the digits
Chief Researcher: Goodwin A W
Duration: 1999 - 2001
Descriptor: NEURON
Research Field Classification: 320705 Sensory Systems


A genetic and functional analysis of the Cb1 proto-oncogene in Drosophila
Chief Researcher: Hime G R
Duration: 1999 - 2001
Descriptor: CANCER
Research Field Classification: 270201 Gene Expression


Integrative properties of intrinsic sensory neurons of the intestine
Chief Researcher: Kunze W A A
Duration: 2000 - 2004
Descriptor: NEURON--GASTROINTESTINAL
Research Field Classification: 320701 Autonomic Nervous System


Visualisation of functionally activated circuitry in the brain
Chief Researcher: Murphy M
Duration: 2001 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Growth factor regulation of neural stem cell commitment and differentiation
Chief Researcher: Murphy M
Duration: 1999 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Regulation of brain development by members of the fibroblast growth factor family
Chief Researcher: Murphy M
Duration: 1999 - 2001
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Role of calcium channels and small-conductance potassium channels in myenteric neurons
Chief Researcher: Vogalis F
Duration: 2001 - 2003
Descriptor: NEURON SIGNALLING
Research Field Classification: 320307 Medical Biochemistry: Other


Role of neurons in the differentiation of gastrointestinal muscle and interstitial cells
Chief Researcher: Young H M
Duration: 1997 - 2001
Descriptor: NEURON--GASTROINTESTINAL
Research Field Classification: 320701 Autonomic Nervous System


Migration and differentiation of enteric neuron precursors
Chief Researcher: Young H M
Duration: 2001 - 2005
Descriptor: NEURON
Research Field Classification: 320701 Autonomic Nervous System

 

Department of Biochemistry and Molecular Biology
http://www.biochemistry.unimelb.edu.au/bch/aboutresearch.htm
[ Australian Science at Work Entry ]

Regulation of focal adhesion kinase by phosphorylation-dephosphorylation
Chief Researcher: Cheng H C
Duration: 2000 - 2002
Descriptor: ENZYME
Research Field Classification: 270805 Genetic Engineering and Enzyme Technology


Characterisation of the activation and lipid binding domains of human apolipoprotein c-II
Chief Researcher: Howlett G J
Duration: 1999 - 2001
Descriptor: PROTEIN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Regulation of glycosylation pathways in parasitic protozoa
Chief Researcher: McConville M
Duration: 1999 - 2003
Descriptor: REGULATION--PROTOZOA
Research Field Classification: 320405 Medical Parasitology


Structure and biosynthesis of Entamoeba histolytica proteophosphoglycans
Chief Researcher: Tull D
Duration: 2001 - 2003
Descriptor: INFECTION
Research Field Classification: 320405 Medical Parasitology


Role of hepatic kinase C-related kinases (PRKs/PKNs) in insulin signalling
Chief Researcher: Wettenhall R E H
Duration: 1998 - 2002
Descriptor: ENZYME CELL SIGNALLING
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides

 

Department of General Practice and Public Health
[ Australian Science at Work Entry ]

Genetics and statistical analysis of case-control-family studies of breast and colorectal cancer
Chief Researcher: Hopper J L
Duration: 1999 - 2003
Descriptor: GENETICS--CANCER
Research Field Classification: 270201 Gene Expression

 

Department of Microbiology and Immunology
http://www.microbiol.unimelb.edu.au/micro/research/research.html
[ Australian Science at Work Entry ]

Building a death-defying islet beta cell
Chief Researcher: Allison J
Duration: 2000 - 2002
Descriptor: DISEASE
Research Field Classification: 320202 Cellular Immunology


Mechanisms of innate immunity to influenza virus
Chief Researcher: Anders E M
Duration: 1997 - 2001
Descriptor: VIRUS--IMMUNOLOGY
Research Field Classification: 320202 Cellular Immunology


Genetics and biochemistry of biosynthesis of the cell wall of mycobacteria
Chief Researcher: Billman-Jacobe H
Duration: 2000 - 2202
Descriptor: CELL WALL--GENE
Research Field Classification: 320401 Medical Bacteriology


The structural basis for the interaction between CD94/NKG2 receptors and HLA class I proteins
Chief Researcher: Brooks A G
Duration: 1999 - 2001
Descriptor: PROTEIN RECEPTORS
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Potent inhibitor of influenza virus: a potential new antiviral?
Chief Researcher: Brown L E
Duration: 2001 - 2005
Descriptor: INFECTION--VIRAL
Research Field Classification: 320402 Medical Virology


HIV-1 selection by dendritic cells in human blood and skin explants
Chief Researcher: Cameron P U
Duration: 1999 - 2001
Descriptor: CELL--HIV
Research Field Classification: 270303 Virology


Evasion of antiviral immunity by latent and productive HIV-1 infection in dendritic cells and macrophages
Chief Researcher: Cameron P U
Duration: 1999 - 2001
Descriptors: HIV CELL--VIRAL
Research Field Classification: 270303 Virology


Dendritic cell manipulation of HIV-1 immunity during DNA vaccination
Chief Researcher: Cameron P U
Duration: 1999 - 2001
Descriptor: HIV
Research Field Classification: 270303 Virology


Direct identification of cytotoxic T cells responding to virus infection
Chief Researcher: Carbone F R
Duration: 1999 - 2001
Descriptor: INFECTION--VIRAL
Research Field Classification: 270303 Virology


Control of the antigen-specific cytotoxic T cell memory response
Chief Researcher: Carbone F R
Duration: 2001 - 2003
Descriptors: IMMUNOLOGY; VIRUS
Research Field Classification: 320202 Cellular Immunology


Apoptosis amongst specific and bystander T cells in chronic bacterial infection
Chief Researcher: Cheers C
Duration: 2001 - 2003
Descriptors: APOPTOSIS; INFECTION
Research Field Classification: 270301 Bacteriology


Cellular and viral components involved in rotavirus entry into cells
Chief Researcher: Coulson B S
Duration: 1998 - 2002
Descriptor: CELL--VIRAL
Research Field Classification: 270303 Virology


Study of plasmodium falciparum var gene function using a tetracycline-controlled gene expression system
Chief Researcher: Crabb B S
Duration: 1999 - 2001
Descriptor: GENE--EXPRESSION
Research Field Classification: 270201 Gene Expression


Functional analyses of the major merozoite surface protein of malaria parasites
Chief Researcher: Crabb B S
Duration: 2001 - 2003
Descriptors: DISEASE--MALARIA; PROTEIN
Research Field Classification: 320405 Medical Parasitology


Synthetic peptides as vaccines
Chief Researcher: Jackson D C
Duration: 1998 - 2002
Descriptors: IMMUNOLOGY--VACCINE; PEPTIDE
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Thymic function in HIV-1 infection
Chief Researcher: Lewin S R
Duration: 2001 - 2003
Descriptors: HIV; INFECTION
Research Field Classification: 270303 Virology


Antigen selection in the MHC-restricted cellular immune response
Chief Researcher: McCluskey J
Duration: 2001 - 2003
Descriptor: IMMUNITY
Research Field Classification: 320202 Cellular Immunology


The role of HLA B27 conformation and expression in ankylosing spondylitis
Chief Researcher: McCluskey J
Duration: 1999 - 2001
Descriptor: DISEASE
Research Field Classification: 270201 Gene Expression


Determinant spreading and the role of the MHC class II region in systemic and organ-specific autoimmunity
Chief Researcher McCluskey J
Duration: 2001 - 2003
Descriptor: IMMUNITY
Research Field Classification: 320205 Transplantation Immunology


Replication control of IncB and other plasmids
Chief Researcher: Praszkier J
Duration: 2001 - 2003
Descriptor: GENE--TRANSCRIPTION
Research Field Classification: 270201 Gene Expression


Pathogenesis of infections with Yersinia enterocolitica
Chief Researcher: Robins-Browne R M
Duration: 2000 - 2002
Descriptor: INFECTION--GASTROINTESTINAL
Research Field Classification: 270301 Bacteriology


A novel viral modifier of TNF family receptor signalling: Elucidation of mechanisms of action
Chief Researcher: Ruby J C
Duration: 2001 - 2003
Descriptor: RECEPTOR SIGNALLING
Research Field Classification: 270303 Virology


The role of apoptosis in pathogenesis and immunology of Salmonella infections
Chief Researcher: Wijburg O L
Duration: 2000 - 2002
Descriptor: IMMUNOLOGY; INFECTION
Research Field Classification: 320401 Medical Bacteriology


The role of apoptosis in pathogenesis and immunology of Salmonella infections
Chief Researcher: Strugnell R A
Duration: 2000 - 2002
Descriptors: APOPTOSIS; INFECTION
Research Field Classification: 270301 Bacteriology

 

Department of Obstetrics and Gynaecology
http://www.obsgyn.unimelb.edu.au/Research/research.htm
[ Australian Science at Work Entry ]

Ovarian cancer metastasis: Unraveling the biology of the plasminogen activation cascade
Chief Researcher: Baker M S
Duration: 2000 - 2002
Descriptor: CANCER MECHANISM
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


The role and regulation of phospholipase isozymes in the initiation of human labour
Chief Researcher: Rice G E
Duration: 2000 - 2004
Descriptor: ENZYME REPRODUCTION
Research Field Classification: 270805 Genetic Engineering and Enzyme Technology

 

Department of Otolaryngology
http://www.medoto.unimelb.edu.au/oto/research.asp
[ Australian Science at Work Entry ]

Binaural hearing and spoken language development in cochlear implant and hearing aid users
Chief Researcher: Blamey P J
Duration: 1997 - 2001
Descriptor: IMPLANT--COCHLEAR
Research Field Classification: 320705 Sensory Systems


Improving speech perception outcomes in deaf adults and children using cochlear implants
Chief Researcher: Busby P A
Duration: 2001 - 2002
Descriptor: INPLANT--COCHLEAR
Research Field Classification: 320705 Sensory Systems


Neural mechanisms underlying temporal and place coding of auditory information in the ventral cochlear nucleus
Chief Researcher: Paolini A G
Duration: 1999 - 2001
Descriptor: NEUROSCIENCE
Research Field Classification: 320307 Medical Biochemistry: Other

 

Department of Paediatrics
http://www.paediatrics.unimelb.edu.au/research.html
[ Australian Science at Work Entry ]

Molecular pathology of human collagen mutations
Chief Researcher: Bateman J F
Duration: 1997 - 2001
Descriptor: GENE--MUTATIONS
Research Field Classification: 270201 Gene Expression


Molecular mechanisms of collagen matrix assembly in health and disease
Chief Researcher: Bateman J F
Duration: 2000 - 2004
Descriptor: DISEASE--PROTEIN COLLAGEN
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Cartilage destruction in arthritis: mechanism of aggrecanase and matrix metalloproteinase action in vivo and in vitro
Chief Researcher: Fosang A J
Duration: 2001 - 2005
Descriptors: DISEASE--ARTHRITIS;--ENZYME
Research Field Classification: 270805 Genetic Engineering and Enzyme Technology


Analysis of aggrecan metabolism by site-directed mutagenesis and neo-epitope technology
Chief Researcher: Fosang A J
Duration: 1997 - 2001
Descriptor: MUTAGENESIS
Research Field Classification: 270804 Genetic Technologies:Transformation, Site-directed Mutagenesis, etc


Growth factor and repulatomy genes?
Chief Researcher: Hasthorp S
Duration: 2001 - 2003
Descriptor: REPRODUCTION--ENDOCRINE
Research Field Classification: 270201 Gene Expression


Analysis of CD95L and TRAIL apoptotic pathways in glioma
Chief Researcher: Hawkins C J
Duration: 2001 - 2003
Descriptor: APOPTOSIS
Research Field Classification: 320307 Medical Biochemistry: Other


The molecular biology of gonad development
Chief Researcher: Sinclair A H
Duration: 1998 - 2002
Descriptor: GENETICS--REPRODUCTION
Research Field Classification: 270201 Gene Expression


The role of SOX14 in limb development and human limb defects
Chief Researcher: Sinclair A H
Duration: 2001 - 2003
Descriptor: GENETICS--DEVELOPMENT
Research Field Classification: 270201 Gene Expression


Use of inhaled antisense oligonucleotides for the treatment of airway inflammation in allergic airway disease
Chief Researcher: Tang M L
Duration: 1999 - 2001
Descriptor: ALLERGY--INFLAMMATION
Research Field Classification: 320307 Medical Biochemisty: Other

 

Department of Pathology
http://www.medfac.unimelb.edu.au/research/
[ Australian Science at Work Entry ]

Novel therapies for Alzheimer's disease based on A-beta - metal interactions
Chief Researcher: Bush A I
Duration: 2001 - 2005
Descriptor: NEURSCIENCE
Research Field Classification: 320702 Central Nervous System


Functional studies on a neuroprotective activity of the amyloid precursor protein of Alzheimer's disease
Chief Researcher: Cappai R
Duration: 2001 - 2005
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


The role of oxidative stress in the patho-aetiology of prion disorders using infected cell culture and animal models
Chief Researcher: Collins S J
Duration: 2000 - 2002
Descriptor: NEUROSCIENCE--ANIMAL MODEL
Research Field Classification: 320403 Medical Infection Agents (incl. Prions)


Identification of novel tumour suppressor gene
Chief Researcher: Cook W D
Duration: 2000 - 2002
Descriptor: TUMOUR--CANCER
Research Field Classification: 270201 Gene Expression


Proteolytic processing of Alzheimer's amyloid precursor: Identification of gamma-secretase
Chief Researcher: Evin G M
Duration: 2000 - 2002
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Extracellular matrix, cell-surface receptors and Alzheimer's disease: A novel glycoform of acetylcholinesterase
Chief Researcher: Small D H
Duration: 2000 - 2004
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Presenilins in Alzheimer's disease
Chief Researcher: Masters C L
Duration: 2000 - 2004
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


How presenilins cause Alzheimer's disease
Chief Researcher: Masters C L
Duration: 1997 - 2001
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Amyloid Abeta in the natural history of Alzheimer's disease
Chief Researcher: Masters C L
Duration: 2001 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Alzheimer's disease: Genetic and environmental clues from BA4 amyloid and its precursor
Chief Researcher: Masters C L
Duration: 1998 - 2002
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


Identification of novel prognostic and therapeutic targets in breast cancer
Chief Researcher: Venter D J
Duration: 1999 - 2001
Descriptors: CANCER--BREAST;--THERAPY
Research Field Classification: 320307 Medical Biochemistry: Other


Investigating the origin and evolution of clonality in neoplasia using a X-activation mosaic mouse
Chief Researcher: Waring P M
Duration: 1999 - 2001
Descriptor: CANCER--MOUSE
Research Field Classification: 270803 Transgenesis

 

Department of Pharmacology
http://www.pharmacology.unimelb.edu.au/pharmwww/research.html
[ Australian Science at Work Entry ]

Modulation of asthmatic airway inflammation by activation of epithelial proteinase activated receptors
Chief Researcher: Anderson G P
Duration: 2000 - 2002
Descriptors: DISEASE; INFLAMMATION; RECEPTORS
Research Field Classification: 270805 Genetic Engineering and Enzyme Technology


Macrophages, sugars and innate immunity in chronic lung inflammation
Chief Researcher: Anderson G P
Duration: 2001 - 2003
Descriptors: DISEASE; INFLAMMATION
Research Field Classification: 320203 Humoral Immunology and Immunochemistry


Mechanisms of protease-activated receptor-2-mediated bronchoprotection
Chief Researcher: Cocks T M
Duration: 2000 - 2002
Descriptor: ENZYME RECEPTOR
Research Field Classification: 270805 Genetic Engineering and Enzyme Technology


Characterisation of PAR2 knockout and transgenic mice: Towards gene therapy for epithelia based inflammatory diseases
Chief Researcher: Cocks T M
Duration: 2001 - 2005
Descriptors: INFLAMMATION; MOUSE--MODEL
Research Field Classification: 270803 Transgenesis


Mechanisms of endothelium and NANC nerve-mediated relaxation of smooth muscle
Chief Researcher: Cocks T M
Duration: 1997 - 2001
Descriptor: CARDIOVASCULAR
Research Field Classification: 320307 Medical Biochemistry: Other


Multiple voltage-sensitive calcium channels in chromaffin cells
Chief Researcher: Marley P D
Duration: 1998 - 2002
Descriptor: CELL--SIGNALLING
Research Field Classification: 320307 Medical Biochemistry: Other


Pharmacological regulation of airway smooth muscle phenotype
Chief Researcher: Stewart A
Duration: 2000 - 2002
Descriptor: PHARMACEUTICAL
Research Field Classification: 320307 Medical Biochemistry: Other


Self-limiting anti-inflammatory actions of glucocorticoids in asthma
Chief Researcher: Stewart A
Duration: 2001 - 2003
Descriptors: DISEASE; ENDOCRINE; INFLAMMATION
Research Field Classification: 320307 Medical Biochemistry: Other


The vasoprotective actions of flavonoids in ischaemia and hypercholesterolaemia
Chief Researcher: Woodman O L
Duration: 2001 - 2003
Descriptors: PHARMACEUTICAL; VASCULAR
Research Field Classification: 320307 Medical Biochemistry: Other

 

Department of Physiology
[ Australian Science at Work Entry ]

Analysis of the Trk-A NGF receptor with highly efficient second generation antisense reagents
Chief Researcher: Barrett G L
Duration: 1999 - 2001
Descriptor: RECEPTOR ANALYSIS
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Properties and electro-physiology of the intrinsic nervous system
Chief Researcher: Bornstein J C
Duration: 2000 - 2002
Descriptor: PHYSIOLOGY--NERVOUS SYSTEM
Research Field Classification: 320703 Peripheral Nervous System


Primary cardiac hypertrophy - a functional genetic approach to investigate cellular mechanisms of metabolic remodelling
Chief Researcher: Delbridge L M
Duration: 2000 - 2002
Descriptor: GENE--CARDIOVASCULAR HYPERTROPHY
Research Field Classification: 270201 Gene Expression


The role of intracellular calcium in the mechanisms of injury, regeneration and plasticity of skeletal muscle
Chief Researcher: Lynch G S
Duration: 1999 - 2001
Descriptor: CELL--SIGNALLING
Research Field Classification: 320307 Medical Biochemistry: Other


The role of renin - angiotensin and growth factors in developmental and pathological neovascularization in the retina
Chief Researcher: Wilkinson-Berka J L A
Duration: 2000 - 2002
Descriptor: ENDOCRINE--VASCULAR
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Regulation of nuclear calcium concentration in the life or death of cells
Chief Researcher: Williams D A
Duration: 2000 - 2002
Descriptor: CELL--SIGNALLING
Research Field Classification: 320307 Medical Biochemistry: Other


Genes encoding the epithelial sodium channel subunits and blood pressure
Chief Researcher: Wong Z Y H
Duration: 2000 - 2002
Descriptor: GENE--CARDIOVASCULAR
Research Field Classification: 270201 Gene Expression

 

Department of Psychiatry
http://www.psychiatry.unimelb.edu.au/research_main.html
[ Australian Science at Work Entry ]

The role of stress, HPA-axis dysfunction and CNS structural and functional change in the development of psychosis
Chief Researcher: McGorry P D
Duration: 2001 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320702 Central Nervous System


A study of the medial temporal lobe in high-risk and established schizophrenia using T2 relaxometry
Chief Researcher: Pantelis C
Duration: 2001 - 2003
Descriptor: NEUROSCIENCE
Research Field Classification: 320307 Medical Biochemistry: Other

 

St Vincent's Hospital and the Geelong Hospital
[ Australian Science at Work Entry ]

Role of platelet derived growth factor in the pathogenesis of renal disease: Effects of in vivo inhibition
Chief Researcher: Gilbert R E
Duration: 1999 - 2001
Descriptors: DISEASE-- ENDOCRINE;--RENAL
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Role of the podocyte in diabetic nephropathy: Structural, functional, molecular and interventional studies
Chief Researcher: Gilbert R E
Duration: 2001 - 2003
Descriptor: DIABETES--RENAL
Research Field Classification: 320307 Medical Biochemistry: Other


A novel inhibitor of osteoclast generation
Chief Researcher: Nicholson G C
Duration: 2000 - 2002
Descriptor: CELL--BONE
Research Field Classification: 320307 Medical Biochemistry: Other


Function and pathophysiological role of a novel glucose transporter expressed in skeletal muscle
Chief Researcher: Best J D
Duration: 2000 - 2002
Descriptor: GLUCOSE--TRANSPORT
Research Field Classification: 320305 Medical Biochemistry: Proteins and Peptides


Generation of vascularised, bioengineered soft tissues
Chief Researcher: Morrison W A J
Duration: 2001 - 2003
Descriptor: TISSUE ENGINEERING
Research Field Classification: 291599 Biomedical Engineering nec

 


Published by the Australian Science and Technology Heritage Centre on AustehcWeb, February 2002
WWW edition
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